Journal of Psychiatry

Frequency of brain tissue donation for research after suicide

28^th International Conference on Psychiatry and Mental Health

November 20-21, 2017 Melbourne, Australia

Rodrigo Chiavaro da Fonseca, Longaray V K, Padoan C S, Goi P D, Vieira D C, Oliveira F H, Kapczinski F and Magalhaes P V

Federal University of Rio Grande do Sul, Brazil

Scientific Tracks Abstracts: J Psychiatry

Abstract:

Obtaining central nervous system tissue is essential for neurobiological research in mental health. There is a growing demand for the availability of human brain tissue, with greater interest in using these tissues for investigation of basic biological processes associated with mental illness. In the current scenario, however, brain tissue biobanks dedicated to psychiatric disorders are extremely scarce. Little is known about organ donation for research. The main reasons and facilitators found for donation to biobanks are: (1) The desire to help others, (2) open dialogue within the family about the organ donation process and (3) a desire to contribute to medical progress. Our objective is to describe the frequency of brain tissue donation for research purposes by families of individuals that committed suicide. We included all requests for brain tissue donation to a brain biorepository made to the families of individuals aged 18-60 years who had committed suicide between March 2014 and February 2016. Cases presenting with brain damage due to acute trauma were excluded. 56 cases of suicide were reported. Of these, 24 fulfilled the exclusion criteria and 11 others were excluded because no next of kin was found to provide informed consent. Of the 21 remaining cases, brain tissue donation was authorized in nine (tissue fragments in seven and the entire organ in two). The sample was composed mainly of men, with a mean age of 39 years. Those responsible for providing informed consent were most often siblings, followed by the children of the tissue donor (Table-1). Donation of brain tissue from suicide cases for research purposes is feasible. The acceptance rate of 42.8% in our sample is in accordance with international data on such donations and similar to rates reported for neurodegenerative diseases. Recent Publications 1. Longaray V K, Padoan C S, Goi P D, da Fonseca R C, Vieira D C, Oliveira F H, Kapczinski F and Magalhaes P V (2017) Frequency of brain tissue donation for research after suicide. Rev Bras Psiquiatr; 39(2): 180-182. 2. Martini M, Fonseca R C, Garbin H I, Bassols A M S (2016) Psychodynamic understanding of "Daenerys Targaryen's" life cycle, character from the series-Game of Thrones. Rev. Bras. Psicoter; 18(1): 55-67.

Biography :

Rodrigo Chiavaro da Fonseca is a Medical student and currently working in multiple projects like “Evaluation of biochemical and molecular parameters of the brain and their clinical correlations in individuals who committed suicide”, “Brazil’s suicide rate from 2000 to 2014 stratified by genre and age” and “Hospital waste: Is it possible to minimize the environmental impact of a big university hospital?”. He is also teaching as Monitor in Promotion and Protection of Elderly and Adults’ Health class and was rewarded with the Award of Best Oral Presentation at the 36th Scientific Week of HCPA in 2016.