Journal of Bioequivalence & Bioavailability

Biochemical analysis and antimicrobial activity of Haemolymph of indian horseshoe crab Tachypleus gigas of chandipur beach in Odisha

3^rd World Congress Bioavailability & Bioequivalence

March 26-28, 2012 Marriott Hotel & Convention Centre, Hyderabad, India

Siddhartha Pati, Smarajit Samal, Sagarika MahaneePrangya priyadarshmee and Bisnu Prasad Dash

Posters: J Bioequiv Availab

Abstract:

T he biochemical composition and anti microbial activity of haemolymph of thirty one adult horseshoe crab (Tachypleus gigas ) of chandipur coast of odisha was studied. The maen haemolymph total glucose,protein,creatinine,cholesterol value were found to be 58.0+_12.6mg/dl,8.9+_2.7gm/dl,0.5+_0.2mg/dl and 0.7+_0.2mg/dl respectively.The mean alkaline phosphate enzyme activity value was 11.7+_1.7u/l.The biochemical composition of T.Gigas was found to be quite similar to the value reported in the limulus polyphemus species of horseshoe crab found along the east coast of USA.The similar haemolymph biochemical environment warrants the possibilities of exploitation of amoebocyte lysate of Indian species for bacterial endotoxin detection in pharmaceutical industries and many sector. The same haemolymph also stop the growth of gram negetive bacteria specially E.Coli due to its antimicrobial activity