Journal of Pharmacovigilance

Assessment of prevalence, incidence and risk management of anticoagulants induced internal bleeding

3^rd International Conference and Exhibition on Pharmacovigilance & Clinical Trials

October 27-29, 2014 Hyderabad International Convention Centre, India

Karthik M S M, Lakshmikanth, Y P Reddy and Mohanraj Rathinavelu

Posters: J Pharmacovigilance

Abstract:

An anticoagulant is a substance that prevents coagulation. Morbidity & mortality associated with an arterial or venous thrombotic event is extremely high. Objective of the current 1 year cross sectional study was to evaluate the prevalence, incidence & risk of anticoagulant use in a secondary care referral hospital of south India. The study was carried out with sources from all WHO causality & severity of reactions, preventability criteria according to Schumock & Thornton scale, determined using Naranjo algorithm & Hartwig questionnaire as standard. Naranjo?s algorithm, WHO UMC causality assessment scale, modified Hartwig & modified Thornton? scale were employed for the causality, severity & preventability assessment of the above said ADR?s. Results as follows according to Hartwig?s severity scale mild ADR?s are 75% and moderate ADR?s are 25%, according to Naranjo causality algorithm 5% are unlikely ADR?s, 50% are possible ADR?s and 45% are probable ADR?s.

Biography :

Karthik M S M currently a student pursuing Doctor of Pharmacy Program in Raghavendra Institute of Pharmaceutical Education & Research (RIPER) affiliated to Jawaharlal Nehru Technological University Anantapur (JNTUA) Anantapuramu, Andhra Pradesh. Active participant and student member of ISPOR - India (International Society for Pharmacoeconomics & Outcome Research, Andhra Pradesh-Regional chapter). He is interested in knowing innovative things in pharmacy practice and to achieve international standards. He is having thirst to know about pharmacovigilance programs.