Diabetes Case Reports

A pilot study on the correlations between Cardiometabolic risk factors and Angiopoietin-like 8 in Saudi women with Type 2 Diabetes Mellitus

7^th Annual Meeting on Diabetes and Endocrinology

November 18, 2024 | Webinar

Walaa Mohammed Saeed

Taibah University, Saudi Arabia

Scientific Tracks Abstracts: J Psychiatry

Abstract:

This study examines whether Angiopoietin Like 8 (ANGPTL8) is linked to cardiometabolic risk factors (CMRFs) in Saudi women with type 2 diabetes (T2DM). Methods: Case-control investigation compared 150 women aged 30â??60 with T2DM to 140 healthy women of the same age and gender. Results: ANGPTL8 levels differed significantly between T2DM and non-diabetics. Fasting blood glucose (FBG), insulin resistance (IR), triglycerides (TG), high-sensitivity C-reactive protein (hs-CRP), body mass index (BMI), and atherogenic index (AIP) of plasma all correlated positively with ANGPTL8 concentrations. Insulin levels correlated negatively with ANGPTL8. Multiple linear regression models showed that elevated ANGPTL8 independently predicted higher FBG, hs-CRP, IR, TG, and AIP in T2DM patients. Conclusion: The study found a significant association between ANGPTL8 levels and IR, hs-CRP, TG, AIP, and BMI in women with T2DM. These components are classified as CMRFs and have the potential to contribute to the development of cardiovascular disease (CVD).

Biography :

I obtained my PhD degree in Clinical Biochemistry from the University of Manchester, UK, within the Faculty of Med ical & Human Sciences. I am presently employed as an Associate Professor at Taibah University in Madinah, Saudi Arabia. Additionally, I have held the position of Vice Dean of the College of Medical Applied Science since 2016. As a Clinical Biochemistry Specialist, I am registered with the Saudi Arabia Commission for Health and hold certification from The American Society for Clinical Pathology (ASCP). An individual in charge of overseeing a scientific experi ence office that focuses on growth and development for health consultations. A manager of a scientific experience office that develops health consultations. My scholarly interests include study ing environmental variablesâ?? effects on liver, pancreatic, GI tract, cardiac, and skin illnesses. GIT and skin microbiota are my research topics. My research focuses on how the liver, pancreas, gastrointestinal tract, and heart system interact in biology and medicine. Endocrine and gastrointestinal systems are involved in metabolic, inflammatory, and infectious disorders including diabetes, fatty liver, liver cirrhosis, cardiovascular disease, hypertension, and obe sity. I focus much of my study on the above health issues, which are major current issues. I have published several research articles in high-impact factor journals.