Health Care : Current Reviews

A comparative cost-effectiveness analysis of intravenous infusion acetaminophen and intramuscular diclofenac for post-hysterectomy pain management: The AIDA study

Joint Event on 39^th European Ophthalmology Congress 11^th World Congress on Health Economics, Health Policy and Healthcare Management

March 18, 2025 Webinar

Akhil Arun1*, Triveni L1, Subhiksha V1, Beulah Milton2 and Gomathy E3

1Amrita Vishwa Vidyapeetham, India 2Krupanidhi College of Pharmacy, India 3MVJ Medical College and Research Hospital, India

Scientific Tracks Abstracts: Health Care Curr Re

Abstract:

Background: After a hysterectomy, efficient pain management is crucial to the healing and comfort of the patient. In order to manage post-hysterectomy pain, this study compared the effectiveness, safety, and costeffectiveness of intramuscular (IM) diclofenac with intravenous (IV) acetaminophen. Methodology: One hundred female patients who met the eligibility requirements for a hysterectomy were prospectively enrolled. Information about the patient's demographics, medical history, hysterectomy type, and current symptoms were noted. For pain relief, patients were randomized to receive IV acetaminophen or IM diclofenac. A standardized scale was used to measure pain at different points after therapy. Cost-effectiveness and adverse medication reactions were assessed as well. Results: When compared to baseline, IV acetaminophen and IM diclofenac both significantly decreased pain scores at all observed time points (p < 0.05). Over the course of 24 hours, IV acetaminophen showed a more persistent analgesic effect. Disparities between the treatments were found by analysing adverse medication reactions; IV acetaminophen was linked to a lower incidence of injection site discomfort and vomiting. IV acetaminophen was regularly found to be more cost-effective than IM diclofenac, according to cost-effectiveness study. Conclusion: Compared to intramuscular diclofenac, IV acetaminophen is the more cost-efficient, safe, and effective analgesic alternative for treating pain following a hysterectomy. These results highlight the value of customized pain management techniques in clinical settings, with ramifications for improving patient outcomes and recuperation.

Biography :

Dr. Akhil Arun is a distinguished academic and researcher in the field of pharmacy, currently serving as a Lecturer in the Department of Pharmacy Practice at the Amrita School of Pharmacy, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kerala, India. Through his dedication to education, research, and clinical practice, Dr. Akhil Arun continues to make significant contributions to the field of pharmacy and healthcare.