The Mean Corpuscular Volume and Hydroxyurea in Brazilian Patients with Sickle Cell Anemia: A Surrogate Marker of Compliance

Ana Maria Mach Queiroz¹, Clarisse Lopes De Castro Lobo¹, Emilia Matos Do Nascimento², Basilio De Bragança Pereira^2,3, Claudia Regina Bonini-Domingos⁴, Gilberto Perez Cardoso⁵ and Samir K Ballas^6*

¹HEMORIO-State Institute of Hematology Arthur de Siqueira Cavalcanti, Rio de Janeiro, Brazil

²Federal University of Rio de Janeiro, COPPE - Postgraduate School of Engineering, Rio de Janeiro, Brazil

³Federal University of Rio de Janeiro-School of Medicine, Rio de Janeiro, Brazil

⁴UNESP - Sao Paulo State University, Department of Biology, Hemoglobin and Hematologic Diseases Genetic Laboratory, São Paulo, Brazil

⁵UFF - Fluminense Federal University, Department of Clinical Medicine, School of Medicine, Niterói, Brazil

⁶Cardeza Foundation, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA