Future Optimal Dosing Regimens for Thrombolysis in Acute Stroke

Kiyoshi Kikuchi^1,2,3,4*, Motohiro Morioka², Yoshinaka Murai¹ and Eiichiro Tanaka¹

¹Division of Brain Science, Department of Physiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan

²Department of Neurosurgery, Kurume University School of Medicine, 67 Asahi- machi, Kurume 830-0011, Japan

³Department of Systems Biology in Thromboregulation, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890- 8520, Japan

⁴Department of Pharmacology, Faculty of Dentistry, Mahidol University, 6 Yothe Road, Rajthevee, Bangkok 10400, Thailand