Hereditary Genetics: Current Research

Brief Exchanges on Selection of Genomic Regions and Genes Related to Adaptation and Fertility Traits of Two Colombian Creole Cattle Breeds

C. De Leon^1* and R. Martinez^{2 1}Department of Genetics, Servicio Nacional de Aprendizaje SENA, Bogotá, Colombia
²Department of Genetics, Corporación Colombiana de Investigación Agropecuaria-Agrosavia, Mosquera, Cundinamarca, Colombia
^*Correspondence: C. De Leon, Department of Genetics, Servicio Nacional de Aprendizaje SENA, Bogotá, Colombia, Email:

Received: 30-Aug-2021 Published: 20-Sep-2021, DOI: 10.35248/2161-1041.21.10.201

Description

Many studies developed in livestock species based on Genome wide association study (GWAS) and other, have led to the discovery of genomics regions and genes involved in the expression of adaptability and fertility traits widely used in selection and conservation programs [1]. Therefore, new selection methods as provided in this study, became essential for the progress in this field, so, the selection signatures and genes found in the genome appears promising with most statically power than the other methods applied in selection programme [2].

Blanco orejinegro (BON) and Sanmartinero (SM) Colombian creole cattle breeds have been genetically characterized by Martínez et al. with limited impact because lacked assessing in depth the variation and genetic differences of these two breeds [3]. Genetic differences can be measured through determination of selection signatures what are genomic regions fixed in the genome as a result of artificial or natural selection for reasons such as adaptability or productivity.

Linkage disequilibrium (LD) was studied in ROMO an BON Colombian creole cattle breed by Bejarano, reporting increasing LD from 0.3 (r²>0.3) in both breeds, similar finding was reported by Li et al., and Pérez O'Brien et al., who also reported LD breaks down rapidly in absence of selection [4-6]. In other Bos taurus breeds, to milk and meat production, have been reported r² ≥ 0.3 at distances less than or equal to 30 Kb (Figure 1 and Table 1) [7,8].

Figure 1: SLinkage disequilibrium variation analysis in the entire genome of Blanco orejinegro and Sanmartinero Breeds. Note the highest peaks corresponding to standardized varLD scores above 4.0, on chromosomes 3, 5, 11, 15, 18, 21, 22, 23, 25 and 29.

Table 1: Genomic regions in base pairs (bp) on chromosomes 3, 5, 11, 15, 18, 21, 23, 29. Linkage disequilibrium variations and standardized varLD scores, on percentiles 0.001 and 0.1 and genes found in these regions.

Genes identified in these selected regions consistent with other research work, are involved in the various biological processes from production, reproduction and adaptation and can be used in selection and conservation programs of these Colombian Creole breeds. This study helps to explain the genetic architecture conformed for productive, reproductive and adaptation processes. Different genes identified in these selected regions consistent with other research work, are involved in the various biological processes from production, reproduction and adaptation and can be used in selection and conservation programs of these Colombian Creole breeds.

REFERENCES

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