Journal of Bioequivalence & Bioavailability

Donna Wang

Donna Wang
Distinguished Professor
Michigan State University, USA

Biography

More than seventy four million American adults suffer from hypertension, a debilitating disease leading to end organ damage including renal failure, heart failure, and stroke. Indeed, 74% of Americans with congestive heart failure have high blood pressure. Our research, using state of the art molecular biological and neurobiological techniques combined with nanotechnology, focuses on elucidating how neuro hormonal systems, in interacting with changing environment, regulates blood pressure and cardiovascular function, and how dysfunction of molecules expressed in the neuro-hormonal systems leads to hypertension and tissue or organ damage including cardiac hypertrophy and infarction. Once key molecules are identified orcharacterized and their mechanisms of action understood, newer and more targeted drugs/interventions may be developed that may accelerate/improve clinical practice of personalized medicine. 

Research Interest

Our research, using state of the art molecular biological and neurobiological techniques combined with nanotechnology, focuses on elucidating how neuro hormonal systems, in interacting with changing environment, regulates blood pressure and cardiovascular function, and how dysfunction of molecules expressed in the neuro hormonal systems leads to hypertension and tissue/organ damage including cardiac hypertrophy and infarction. Once key molecules are identified characterized and their mechanisms of action understood, newer and more targeted drugs/interventions may be developed that may accelerate/improve clinical practice of personalized medicine.