Indexed In
- Academic Journals Database
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- China National Knowledge Infrastructure (CNKI)
- Ulrich's Periodicals Directory
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Zhi Su
Immunology Discovery, Abbvie Inc., North Waukegan Road, North Chicago, IL 60064, USA
Publications
-
Review Article
Cellular, Molecular, and Pharmacological Characterization of a House Dust Mites (HDM)-Induced Murine Model of Dermatitis
Author(s): Zhi Su
Background: House Dust Mites (HDM), common allergens that can induce Atopic Dermatitis (AD), are widely employed to generate mouse models of AD. In the current study, we compared the AD-like phenotypes between two mouse strains, NC/Nga, and BALB/c, in response to HDM, and performed cellular, molecular, and pharmacological characterization of HDM-induced dermatitis in NC/Nga mice. Methods: In-life endpoints (skin clinical scores, ear thickness, Transepithelial Water Loss (TEWL), scratching bouts) and terminal endpoints (histopathology, total serum IgE and tissue cytokines) were measured. Further phenotyping of NC/Nga was performed by flow cytometry, gene expression analysis, and pharmacology. Results: HDM applications resulted in a more robust AD-like dermatitis in NC/Nga than BALB/c mice as evidenced by greater cha.. View more»