Journal of Vascular Medicine & Surgery

Department of Neuroscience, Michigan Institute of Neuroscience, University of Michigan, Ann Arbor, USA

Publications

• Research Article   
  Morphometric Interpretation of Postganglionic Sympathetic Neurons that Innervate Myocardium
  Author(s): Sachin Sharma* and Vivek Kumar
  
  Background and aims: The sympathetic nervous system modulates cardiac functions through neurotransmitters such as neuropeptide-Y and galanin released by postganglionic neurons. Hence, we hypothesize that dendritic and axonal morphological architecture of cardiac-innervating neurons might reflect the communicating input and output signals either within the postsynaptic neurons or to the adjacent myocardial cells. Methods: In the current study, we carried-out morphometric analyses of cardiac-innervating neurons, measuring dendritic size, shape, and neuronal-polarity. We used retrograde tracers (adeno-associated virus conjugate to fluorophores) injected either from left-ventricular myo-cardial tissue or fore-limb skin tissue-beds. Stellate ganglia were harvested from the mice for imaging and morphometric analysis. Results.. View more»
  

  DOI: 10.350310/2329-6925.25.13.596

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