Department of Material Science, Tsinghua University, China
Mini Review
Emergence of Data-Driven Microfluidics.
Author(s): Takasaki Yumi
Microfluidic devices currently rely on researchers to select the initial operating conditions empirically, then monitor and
modify parameters throughout studies to achieve and maintain stable conditions that produce repeatable data. Multiple factors
can cause inconsistent experimental conditions in polydimethylsiloxane-based microfluidic devices, including fabrication
flaws, clogging, bubble formation, chemical impurities, or long-term effects like temperature and pressure fluctuations, surface
fouling, and substrate deformation. Because of the adsorption of hydrophobic small molecules, these differences can alter
chemical synthesis by changing solution concentrations or biological analyses. In this section, we discuss new research on
the application of machine intelligence in microfluidic chips in conjunction with optical microscopy. This method has been
used to .. View more»