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OD Oshan Abu
Department of Biochemistry, University of Benin, Edo State, Nigeria
Publications
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Research Article
Ethanol Leaf Extract of Anacardium occidentale Ameliorates Alloxan Induced Changes on Blood Glucose Level and Lipid Profile of Wistar Rats
Author(s): OD Oshan Abu*, KE Imafidon and O Obayuwana
Background: It is estimated that by the year 2030 the number of persons with Diabetes Mellitus (DM) would increase to 366 million. Diabetes Mellitus (DM) is a condition primarily defined by the level of hyperglycemia giving rise to risk of microvascular damage (retinopathy, nephropathy and neuropathy). Aim: To investigate the effect of aqueous leaf extract of Anacardium occidentale on blood glucose level and lipid profile of diabetic rats. Methods: Adult male Wistar rats (n=30) weighing 150 g-200 g (mean weight=175 g ± 25 g) were randomly assigned to 6 groups (5 rats/group): Normal control, diabetic control and Dimethyl Sulfoxide (DMSO), metformin, extract and treatment groups. Diabetes Mellitus (DM) was induced via intraperitoneal injection of freshly prepared alloxan monohydrate solu.. View more»