Department of Internal Medicine, Fujiidera Municipal Hospital, Fujiidera, Japan
Research Article
The Effect of Oral Semaglutide on Urinary Albumin to Creatinine Ratio in Patients with Type 2 Diabetes
Author(s): Masahiro Yano*, Sadahiko Uchimoto, Masami Nishimura and Saori Yamaguchi
Background: Oral semaglutide has been shown to have excellent effects such as reduction of HbA1c and weight loss.
However, there are no reports of the effect of oral semaglutide on Urinary Albumin to Creatinine Ratio (UACR).
In this study, we investigated the effect of oral semaglutide on UACR in patients with type 2 diabetes who switched
from Dipeptidyl Peptidase-4 (DPP4) inhibitors to oral semaglutide.
Method: Thirty patients with type 2 diabetes (15 males, 15 females, average age 60.3 years old), whose UACR was
measured before and after switching from DPP4 inhibitors to oral semaglutide, were investigated. It was compared
between before and after 6.6 months on averages that body weight, systolic and diastolic blood pressure, HbA1c,
Low-Density Lipoprotein Cholesterol (LDL-C), and UACR.
Result: Afte.. View more»