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Lisa Hadson
Agency for Healthcare Research and Quality, United Kingdom
Publications
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Short Communication
Buruli Ulcer: A Neglected Exotic Bacterial Infection of The Skin and Soft Tissue
Author(s): Lisa Hadson*
Buruli Ulcer (BU) is a necrotizing and handicapping cutaneous infection caused by Mycobacterium ulcerans, one of the skinrelated neglected tropical diseases (skin NTDs). It is an arising human sickness brought about by disease with a sluggish developing microorganism, Mycobacterium ulcerans that produce mycolactone, a cytotoxin with immunomodulatory properties. The mycobacteria produce mycolactones that cause tissue necrosis. The sickness is related to wetlands in certain tropical nations, and evidence for the role of insects in the transmission of this pathogen is growing. Near genomic examination has uncovered that M. ulcerans emerged from Mycobacterium marinum, an omnipresent quickly developing sea-going species, by flat exchange of a harmfulness plasmid that conveys a group of qualities for mycolactone creation, trailed by reductive .. View more»