Department of Radiology, Nihon University School of Medicine, Tokyo, Japan
Review Article
Long COVID in pediatric and young adult patients: a review of evaluation for microvascular changes, endothelial dysfunction, and arterial stiffness
Author(s): Kazumi Fujioka*
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) reservoirs in most tissues may be underlying endotheliitis in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). The vascular changes of the microcirculation with persistent capillary rarefication and endothelial dysfunction have already been demonstrated in adult patients with PASC. In this review, the author outlined the current knowledge and trends of long COVID-19 for evaluation of microvascular changes, endothelial dysfunction and arterial stiffness in pediatric and young adult patients. The Medical Literature Analysis and Retrieval System Online (MEDLINE)/PubMed and Excerpta Medica dataBASE (EMBASE) data-bases were systematically searched for studies using microvascular, endothelial, and Arterial Stiffness (AS) dysfunction in pediatric and young adult patients with long COVID. In addition, the therapeutic strategies f.. View more»