Journal of Vascular Medicine & Surgery

Department of Neurosurgery, Changzhou Second People's Hospital Affiliated to Nanjing Medical University, Changzhou, China

Publications

• Mini Review   
  Impact of Albumin and Fibrinogen on Early Brain Injury
  Author(s): Fang Liu*, Hao Ran Wang, Jie Ma, Yi Zhuo Guo, Ke Feng Liu, Bin Han, Ming Hai Wang, Fei Hui Zou, Jian Wang, Zhen Tian, He Qi Qu and Xian Long Huang
  
  Cerebral Aneurysmal Subarachnoid Hemorrhage (aSAH) is a major cause of hemorrhagic stroke worldwide, with an annual incidence of 9 per 100,000 people, accounting for approximately 85% of Subarachnoid Hemorrhages (SAH). Once an aneurysm ruptures, there is a high risk of early patient mortality, emphasizing the need for prompt treatment. Surgical intervention can successfully treat a ruptured aneurysm and reduce the risk of rebleeding; however, 20% to 30% of patients may experience focal neurological or cognitive impairments. In patients with subarachnoid hemorrhage, early hypoalbuminemia is an independent predictor of hospital death. Albumin levels after subarachnoid hemorrhage have a time-dependent connection with death, with a stronger correlation with early mortality than with late mortality. Fibrinogen, spilling through the compromised blood-brain barrier, reaches the brain parench.. View more»
  

  DOI: 10.35248/2329-6925.24.12.551

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