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Hayley Martine
Department of Thrombosis and Vascular Diseases Laboratory, RMIT University, Bundoora, Victoria, Australia
Publications
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Research Article
Application of the Doppler Ultrasound in Detecting Foetal Anaemia caused by Anti-Kell Maternal Alloimmunisation: Systematic Review and Meta-Analysis
Author(s): Hayley Martine and Denise E. Jackson*
Background: Past studies have examined the Doppler ultrasounds ability to detect foetal anemia however few focus on Anti-Kell, rather centring on maternal alloimmunisation as a whole. Anti-Kell has proven to be clinically significant in Haemolytic Disease of the Foetus and Newborn (HDFN) due to the suppression of erythroid progenitor cells and the absence of typical signs of anemia. For these reasons, regular procedures to detect foetal anemia are unreliable with Anti-Kell. Therefore, a systematic review and meta-analysis was performed to investigate the reliability of the Doppler ultrasound in Kell-sensitised pregnancies. Methods: PubMed, SCOPUS, Google Scholar and ProQuest were searched from January 2012 to August 2022 for eligible Doppler ultrasound studies with Anti-Kell specific data. A manual search was performed using .. View more»