Journal of Blood Disorders & Transfusion

Department of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia

Publications

• Research Article   
  The Significance of Immune and Non-immune Causes Associated with Platelet Refractoriness in Haemato-oncology Patients: A Systematic Review and Meta-Analysis
  Author(s): Xiangyu Long and Denise E. Jackson*
  
  Platelet Transfusion Refractoriness (PTR) can be defined as failed to elevate the level of platelet after receiving repeated platelet transfusion. PTR can be seen in normal patients as well as haemato-oncology patients when treating thrombocytopenia and it’s related to increased morbidity and mortality rate. Various risk factors can lead to PTR development, including both immune and non-immune factors. There was no comprehensive review of risk factors associated with PTR in haemato-oncology patients previously. Therefore, this study aims to determine the significance of both immune and non-immune causes associated with PTR in patients with haematological malignancies. The systematic review was conducted with relevant articles searched from five databases from 2003 to 2023. The meta-analysis was conducted using Open Meta Analyst software with one-arm proportion (arcsine transform.. View more»
  

  DOI: 10.4172/2155-9864.24.15.579

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