Department of Nutrition Ibero- american University Foundation, Barcelona, Spain
Research Article
Evaluation of a DNA-Based Screening Method for People at High Risk of Developing Diabetes in the Dominican Republic
Author(s): Arreguín Andrea*, Borbon Glenda, Orozco Bernardo and Migliaccio Dominic
Aim: The purpose of this research was to evaluate the effectiveness of DNA testing as a diabetes screening instrument
for high-risk patients of developing diabetes.
Methods: Patients at of High-Risk (HR) and Low-Risk (LR) for developing Diabetes Mellitus (DM) according to risk
factors established by the American Diabetes Association were divided into two groups, HR and LR. Both groups
underwent nutrigenetic (PPARG, SLC2A2, Transcription Factor 7-Like-2 (TCF7L2), FTO genes), HOMA-IR score,
and medical history screening. 26 patients were in the HR group and 38 were in the LR group.
Results: The mean age of participants in HR group was 47 (± 8.37) and 43 years (± 10.57) in the LR group, 69% of
participants were male and 53% were female, respectively. In both groups, .. View more»