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Aziz Rodan Sarohan

Department of Obstetrics and Gynecology, Baglar Private Hospital, Shagreen Health Life Sciences, Diyarbakır, Turkey

Publications
  • Review Article   
    New Strategies for COVID-19 Vaccination and Adjuvant Prophylaxis
    Author(s): Aziz Rodan Sarohan*

    Although more than a year has passed since the outbreak of the COVID-19 pandemic, the pathogenesis of the disease has not yet been clarified. For this reason, no significant improvement has been achieved regarding the treatment of the disease. The way to develop effective vaccines and drugs against COVID-19 is also through a clear understanding of the pathogenesis. The very frequent mutating nature of SARS-CoV-2 and the emergence of new variants have raised concerns that vaccines against COVID-19 may not work. In the defense mechanism of COVID-19, retinol and retinoic acids are used in the synthesis of Type I interferon and suppression of inflammation. However, due to the extremely large viral genome in COVID-19, retinol is used too much and is consumed quickly. Due to the retinoid signaling defect that develops, as a result, both Type I interferon synthesis is inter.. View more»

    DOI: 10.35248/2157-7560.21.12.449

    Abstract HTML PDF