Journal of Blood Disorders & Transfusion

Y. Perel

Publications

• Research Article
  Revisiting Splenectomy in Childhood Immune Thrombocytopenic Purpura in the Era of New Therapies: The French Experience
  Author(s): Nathalie Aladjidi, Raoul Santiago, Corinne Pondarré, Anne Lambilliotte, Guy Leverger, Claire Godard Sebillotte, Vincent Barlogis, Pierre Rohrlich, Marlène Pasquet, Sophie Bayart, Dominique Plantaz, Patrick Lutz, Karine de Bosredon, Aude Marie-Cardine, Corinne Guitton, Patrick Boutard, Martine Munzer, Jean-Louis Stephan, Thierry Leblanc and Y. PerelNathalie Aladjidi, Raoul Santiago, Corinne Pondarré, Anne Lambilliotte, Guy Leverger, Claire Godard Sebillotte, Vincent Barlogis, Pierre Rohrlich, Marlène Pasquet, Sophie Bayart, Dominique Plantaz, Patrick Lutz, Karine de Bosredon, Aude Marie-Cardine, Corinne Guitton, Patrick Boutard, Martine Munzer, Jean-Louis Stephan, Thierry Leblanc and Y. Perel
  
  Objective: While splenectomy is the gold standard treatment for refractory primary immune thrombocytopenia (ITP) in adult, its place remains debated in children. The French Rare Disease Plan provided us the opportunity to conduct a collaborative study of the efficiency and tolerance of this procedure in childhood ITP. Patients and methods: A retrospective study was conducted in France in order to identify children with ITP treated with splenectomy during a 9-year period. A total of 78 children were included. Data from the ongoing CEREVANCE national cohort of childhood auto-immune cytopenia in 30 units were reviewed and completed by a direct contact with the referent physicians. International terminology for response definition was used. Relapsefree survival was assessed by the Kaplan-Meier method. Results: The medi.. View More»
  DOI: 10.4172/2155-9864.S3-003

  Abstract PDF