Journal of Liver

Xia Xuefeng

Biography

Xuefeng Xia is Currently working as a Principal Investigator in Center for Diabetes Research ,The Methodist Hospital Research Institute.He is awarded postdoctora in Baylor College of Medicine in 2002 . His international experience includes various programs, contributions and participation in different countries for diverse fields of study.  Dr. Xuefeng Xia joined the University of Texas Health Science Center at Houston as an instructor. Dr. Xia was appointed to assistant professor of medicine at the University of Texas Health Science Center in 2006. He was appointed assistant member at The Methodist Hospital Research Institute in 2008. Dr. Xia also holds an adjunct professorship at The Guangzhou Medical University in China. His research interests in His research projects focus on liver and kidney disease function and disease states, and span the Genomic Medicine and Diabetes & Metabolic Disease research programs reflects in his wide range of publications in various national and international journals.  Dr. Xia is also a member of American Gastroenterology Association and The Endocrine Society.    

Research Interest

Dr. Xia’s research defines the role and molecular mechanisms of nuclear hormone receptors in the liver and kidney. His lab uses multidisciplinary state-of-the-art technologies including genetically modified mouse models, genomic array, proteomics, metabolomics, 3-D cultures, and molecular, cellular and histological methodologies. The three key goals of Dr. Xia’s research are: -To use manipulation of nuclear receptor function to control bile physiology in cholestatic liver disease, gallstone formation, and cholangiocarcinoma -To use liver secreted hormone to influence metabolic pathways important in lipid and glucose meta-bolism, lipolysis and regulation weight. -To develop a method to reproducibly isolate highly-enriched podocytes from mouse glomeruli to identify novel podocyte genes and pathways that are altered by kidney injuries