Cardiovascular Pharmacology: Open Access

Tsenum JL

Publications

• Research Article
  Antihyperlipidemic Effect of Solanum incanum on Alloxan Induced Diabetic Wistar Albino Rats
  Author(s): Tsenum JLTsenum JL
  
  The effect of orally administered aqueous fruit extract of Solanum incanum on serum lipid profile of Wistar Albino rats were determined. Twelve male and female Wistar Albino rats were randomly assigned into four groups of three rats each, following acclimatization to laboratory and handling conditions. Diabetes was induced with a single dose of alloxan (120 mg/kg) body weight and plasma glucose was taken 72 h after induction to confirm diabetes. The normal control was not induced. Animals in group a (normal control) and B (diabetic) were administered 0.5 ml of normal saline respectively. Group C was administered with 10 mg/kg weight of glibenclamide and group D was administered 500 mg/kg body weight of aqueous Solanum incanum extract. Extract administration lasted for fourteen days. Water and feeds were allowed ad libitum. After the two weeks treatment with the plant extract, blood sa.. View More»
  DOI: 10.4172/2329-6607.1000239

  Abstract PDF