Journal of Pharmacovigilance

Tomoko Umeda

Publications

• Research Article
  Breath Alcohol Concentration in Japanese Breast Cancer Patients Following Alcohol-Containing Chemotherapeutic Agent Infusion
  Author(s): Naoko Itoi, Hajime Abe, Tsuyoshi Mori, Yuki Kawai, Yoshihiro Kubota, Tomoko Umeda and Tohru Tani Naoko Itoi, Hajime Abe, Tsuyoshi Mori, Yuki Kawai, Yoshihiro Kubota, Tomoko Umeda and Tohru Tani
  
  Background: Preparations containing dehydrated ethanol as an additive, due to its water-insoluble properties, have been frequently used for chemotherapeutic agents, such as paclitaxel (PTX), docetaxel (DOC) and eribulin. When selecting these drugs, the influence of alcohol on the central nervous system (CNS) must be considered. In this study, we measured the breath alcohol concentration (BAC) in Japanese breast cancer patients treated with these agents. Method: Japanese patients with breast cancer receiving outpatient chemotherapy with alcohol-containing agents were registered. The BAC was measured immediately after drip infusion and 30 and 60 minutes later. Result: Thirty-one female patients were enrolled in this study. Breath alcohol was detected in 18 patients (58%) immediately after .. View More»
  DOI: 10.4172/2329-6887.1000138

  Abstract PDF