Advances in Pharmacoepidemiology and Drug Safety

Stephen B Edge

Publications

• Research Article
  Cholesterol Drugs Improve Breast Cancer Prognosis in Women with Diabetes Mellitus
  Author(s): Chi-Chen Hong, Anand B Shah, Caitlin M Jackowiak, Ellen Kossoff, Hsin-Wei Fu, George K Nimako, Dimitra Bitikofer, Stephen B Edge and Alice C Ceacareanu Chi-Chen Hong, Anand B Shah, Caitlin M Jackowiak, Ellen Kossoff, Hsin-Wei Fu, George K Nimako, Dimitra Bitikofer, Stephen B Edge and Alice C Ceacareanu
  
  Study objective: To evaluate the impact of Cholesterol management on breast cancer recurrence and survival (CHOLBRES) in diabetic women with breast cancer. Design: Cholbres study included all incident breast cancer cases with pre-existing diabetes mellitus diagnosed with cancer between 01/01/2003-12/31/2007. Clinical characteristics, outcomes, and pharmacotherapy were abstracted from medical records or hospital-developed databases. The follow-up, with a median of 31 months, began at breast cancer diagnosis and ended at first recurrence, death, or date of last contact. Patients: All diabetes mellitus women with incident breast cancer were identified (n=269); of these 208 met the inclusion criteria and were used for analysis. Methods: The association between self-reported cholesterol-lowering medications and breast cancer outcomes was evaluated with.. View More»
  DOI: 10.4172/2167-1052.1000130

  Abstract PDF