Shao-Liang  Chen
	
					    												Nanjing First Hospital, 
Nanjing
China						                            
                            
						
 Research Article
												Bioequivalence Study of Clopidogrel 75 Mg Tablets in Healthy Male
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Author(s): Jian-Jun  Zou, Jie  Tan, Hong-Wei  Fan and Shao-Liang  ChenJian-Jun  Zou, Jie  Tan, Hong-Wei  Fan and Shao-Liang  Chen             
						
												
				 The marked inter-individual and ethnic variabilities in the metabolism  of clopidogrel has been investigated.               Although the pharmacokinetics (PK) of clopidogrel has been  reported previously in Whites and Korean volunteers,               the PK characteristics may not be fully extrapolated to  the Chinese population. Little is known about the PK               characteristics and relative bioavailability of  clopidogrel in Chinese population. The present study was to assess               the PK characteristics and relative bioavailability of  clopidogrel in healthy Chinese volunteers. A single-dose,               randomized-sequence, open-label, 2-period crossover study  was performed in fasting healthy Chinese male               volunteers. Eligible subjects were randomly assigned to  receive a single 75-mg dose of the test or reference               formulation of clopid.. View More»
				  
												DOI:
												 10.4172/jbb.1000102