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Shahana A Choudhury
Shahana A Choudhury
Associate Professor of Pediatrics, Meharry Medical College, Department of Pediatrics, 1005 Dr. D.B. Todd Jr. Blvd., Nashville, TN 37208,
Tanzania
Publications
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Research Article
Seroprevalence of Antibodies to Measles, Mumps and Rubella (MMR) Vaccines in Previously Vaccinated Human Immunodeficiency Virus-Infected Children and their Control Counterparts
Author(s): Shahana A Choudhury and Fazle MatinShahana A Choudhury and Fazle Matin
Background: Concerns remain regarding immunity to measles, mumps and rubella in HIV-infected children and need for booster doses during later adolescent-hood or young adulthood. Methods: We evaluated measles, mumps and rubella antibodies in 13 HIV- infected and 13 age-matched control children. All children had received 2 doses of the measles, mumps and rubella (MMR) vaccine. Anti-measles, mumps, and rubella antibody levels were assessed by ELISA at a mean of 30 months in the HIV-infected group and 27 months in the control children, following a second dose of the MMR vaccine. MMR antibodies considered to be protective levels were >1.1 ODR (Optical Density Ratio) for measles and mumps and >9.9 IU/ml for rubella. Results and Conclusions: Of the thirteen HIV-infected children, only four (31%) (p=0.01) had protective level (>1.11 ODR) of antibodies to measles and five (38%) (p=0.0.. View More»
DOI: 10.4172/2157-7560.1000255