Journal of Blood Disorders & Transfusion

Salwa Zaghloul

Publications

• Review Article
  Thrombotic Thrombocytopenic Purpura Refractory to Plasmapheresis Treated Successfully with Vincristine: A Case Report
  Author(s): Walid H. Elrewihby, Salwa Zaghloul, Nivin Saber, Emad Eldin Hasan and Adel ElattarWalid H. Elrewihby, Salwa Zaghloul, Nivin Saber, Emad Eldin Hasan and Adel Elattar
  
  Introduction TTP is a life-threatening clinicopathologic disorder involving multiple organ systems, which remains a management challenge to physicians. If not treated promptly, TTP typically follows a progressive deteriorating course with irreversible renal failure, progressive neurologic deterioration, cardiac ischemia, and death. The immediate administration of plasma exchange has been the essential and urgent treatment for patients with a clinical diagnosis of TTP The reported incidence of patients who do not respond to plasma exchange (PE) [refractory TTP] and require additional therapy varies between 10% and 42%. Case report We have described a 24 year female patient of TTP who remained refractory after 27 sessions of PE combined with corticosteroids. We added a slow infusion of 2mg Vincristine (VCR) and followed by .. View More»
  DOI: 10.4172/2155-9864.1000380

  Abstract PDF