Ramzy S
Egypt
Research Article
Effect of Antibiotic Combinations on the Sensitivity of Carbapenem
Resistant Acinetobacter baumannii Strains
Author(s): Elhabibi T and Ramzy SElhabibi T and Ramzy S
Acinetobacter baumannii is one of the predominant pathogens involved in hospital acquired infections worldwide. Despite intensive surveillance and preventive measures, these infections are major cause of high mortality rates. In this study a total of 375 A. baumannii isolates were isolated from a variety of clinical collected from 5 different hospitals in Great Cairo. These isolates were identified as A. baumannii biochemically, by API20E system and genetically by detection of 16S rRNA gene. All isolates showed positive results and confirmed for the presence of the suspected gene by PCR. The antibiotic susceptibility patterns for the isolated A. baumannii were also evaluated. The detection of the presence of OXA-type (OXA 23, 24, 51 and 58) carbapenemases-encoding genes which are responsible for carbapenem resistance was also performed. I observed the presence of OXA 23 gene in 84% of.. View More»
DOI:
10.4172/1948-5948.1000356