Journal of Allergy & Therapy

Pawan Malik

Publications

• Research Article
  A New Class of Polymeric Anti-Allergen Nasal Barrier Film Solution for the Treatment of Allergic Rhinitis
  Author(s): Lea Shrivastava, Hendrik Schütte, Pawan Malik and Ravi ShrivastavaLea Shrivastava, Hendrik Schütte, Pawan Malik and Ravi Shrivastava
  
  Objective: Allergic rhinitis (AR) is oversensitivity of nasal mucosa to allergen exposure leading to IgE-mediated nasal mucosal inflammation and cellular destruction. Applying any chemical drug over the nasal mucosa may provide symptomatic relief but at the same time the presence of chemicals, such as cortisones and antihistaminic, hampers mucosa repair and, in consequence, cellular defense functions. Therefore, cleaning, avoiding allergen exposure, and protecting nasal mucosa from contact with allergens with a cell-friendly mechanical device, could be an effective remedy to treat allergic rhinitis. Methods: A double blind, randomized, placebo controlled, multicenter clinical trial was conducted in patients suffering from severe AR. 15 patients were treated with saline as comparator product (CP) versus 31 treated with the test product (TP). .. View More»
  DOI: 10.4172/2155-6121.1000263

  Abstract PDF