Clinics in Mother and Child Health

Patrice Malard

Publications

• Research Article
  SN2-Palmitate Improves Crying and Sleep in Infants Fed Formula with Prebiotics: A Double-Blind Randomized Clinical Trial
  Author(s): Fabiana Bar-Yoseph, Yael Lifshitz, Tzafra Cohen, Patrice Malard, Zailing Li, Hong Cui, Aimin Zhang, Jing-Lan Wu and Chundi XuFabiana Bar-Yoseph, Yael Lifshitz, Tzafra Cohen, Patrice Malard, Zailing Li, Hong Cui, Aimin Zhang, Jing-Lan Wu and Chundi Xu
  
  Background and Aim: Palmitic acid (PA, C16:0), one of the major saturated fatty acids in human milk fat being 17-25% of the fatty acids, is esterified mainly at the SN2-position (SN2-palmitate). Contrary in vegetable oils, which are commonly used as fat source in infant formulas, PA is esterified mainly at the outer positions, i.e, SN1 and SN3 positions, resulting in reduced fat absorption and harder stools. SN2-palmitate and prebiotics have been shown to improve digestion and reduce stool hardness. Our aim was to study the potential effects of SN2-palmitate in addition to prebiotics in formula-fed Chinese infants. Methods: 171 healthy term infants were included (within 14 days from birth) in the study. Formula-fed infants were randomly assigned to receive either SN2-palmitate containing formula (INFAT®, Advanced Lipids), (n=57) or .. View More»
  DOI: 10.4172/2090-7214.1000263

  Abstract PDF