Journal of Pharmacovigilance

Paola Lucia Minciullo

Publications

• Review Article
  Systematic Review of Tranexamic Acid Adverse Reactions
  Author(s): Gioacchino Calapai, Sebastiano Gangemi, Carmen Mannucci, Paola Lucia Minciullo, Marco Casciaro, Fabrizio Calapai, Maria Righi and Michele NavarraGioacchino Calapai, Sebastiano Gangemi, Carmen Mannucci, Paola Lucia Minciullo, Marco Casciaro, Fabrizio Calapai, Maria Righi and Michele Navarra
  
  Background : Tranexamic acid is a synthetic lysine derivate that exerts its antifibrinolytic effect by reversible blocking lysine binding sites on plasminogen preventing fibrin degradation. It is widely used for haemorrhage or risk of haemorrhage in increased fibrinolysis or fibrinogenolysis. Aim: The aim of our work was to review the literature regarding the best evidence on tranexamic adverse reactions and to describe them according to the apparatus involved. Methods: The literature was searched for publications on tranexamic acid adverse reactions, adverse events, using MEDLINE, Scopus, Embase, Web of Science and Google Scholar. Results: In the light of the results, seems to be.. View More»
  DOI: 10.4172/2329-6887.1000171

  Abstract PDF