Pharmaceutica Analytica Acta

Nir Edery

Publications

• Review Article
  Tremor-Salivation Syndrome in Canine following Pyrethroid/Permethrin Intoxication
  Author(s): Sigal Klainbart, Yael Merbl, Efrat Kelmer, Olga Cuneah, Nir Edery and Jakob A ShimshoniSigal Klainbart, Yael Merbl, Efrat Kelmer, Olga Cuneah, Nir Edery and Jakob A Shimshoni
  
  A 17-month-old male King Charles cavalier was presented with acute onset of generalized body tremors, facial twitching and salivation after being exposed to 2 different classes of compounds of the pyrethrins/pyrethroids group as well as to imidacloprid. Bifenthrin toxicity was confirmed by gas chromatography mass spectrometry. Pyrethroid toxicosis in dogs is to the best of our knowledge rarely reported in the literature. The dog displayed neurological signs highly characteristic of Tremor-Salivation-syndrome associated with pyrethroid toxicosis. The plasma half-life of bifenthrin in dogs was 7.6 hr). Initial therapy consisted of diazepam, methocarbamol and IV fluids, followed by general anesthesia with isofluran and diazepam CRI. Supportive nursing care was provided as needed. Twenty-four hours post admission, the dogs was no longer under general anesthesia. Seventy two hours post admiss.. View More»
  DOI: 10.4172/2153-2435.1000320

  Abstract PDF