Journal of Blood Disorders & Transfusion

Nicolas J. Mouawad

Publications

• Research Article
  Anemia and Transfusions in Surgical Patients: Current Concepts and Future Directions
  Author(s): Stefan W. Leichtle, Nicolas J. Mouawad and Joseph J. Bander Stefan W. Leichtle, Nicolas J. Mouawad and Joseph J. Bander
  
  Anemia is a frequent finding during routine assessment of patients prior to elective surgery. In this setting, anemia has been demonstrated to be a risk factor for negative post-operative outcomes as well as increased intra- and postoperative transfusion requirements. Historically, blood products were given in abundance to surgical patients, based on liberal “transfusion triggers”, i.e. mildly decreased hemoglobin or hematocrit levels prompted the transfusion of blood. Current guidelines propose a more restrictive approach for surgical patients, reflecting the increased recognition of complications of blood products beyond hemolytic transfusion reactions and disease transmission. Transfusionrelated acute lung injury, immunosuppression, alloimmunization, and even increased recurrence of malignancies have been associated with the administration of blood transfusion.. View More»
  DOI: 10.4172/2155-9864.S1-002

  Abstract PDF