Journal of Blood Disorders & Transfusion

Najmaddin Khoshnaw

Publications

• Case Report
  Spontaneous Life Threatening Massive Retroperitoneal and Iliopsoas Hemorrhages in Adult Hemophilia - A Patients with Inhibitor - Case Series
  Author(s): Najmaddin Khoshnaw, Belal A. Muhammad and Ahmed k. YassinNajmaddin Khoshnaw, Belal A. Muhammad and Ahmed k. Yassin
  
  Spontaneous retroperitoneal and iliopsoas muscle hemorrhages are rare bleeding episodes in hemophilia patients. Their diagnosis requires high degree of clinical suspicion because presentation may mimic other abdominal and pelvic disorders. These bleedings in severe hemophilia-A patients with factor VIII inhibitor are associated with high morbidity and mortality as control of hemostasis in these cases is challenging. Herein we report 4 adult patients with known congenital Hemophilia-A and factor VIII inhibitor. One of the patients had gigantic retroperitoneal hemorrhage presented with subsequent increase in abdominal pain. The other three patients had significant iliopsoas hemorrhage presented with groin pain. All the events were spontaneous and nontraumatic. These patients were treated with recombinant activated factor VII (rFVIIa) in a dose of 90 μg/kg. Treatment with rF.. View More»
  DOI: 10.4172/2155-9864.1000261

  Abstract PDF