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Mustapha Mecili
Mustapha Mecili
France
Publications
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Review Article
The Syndrome of Food-Cobalamin Malabsorption: A Personal View in a Perspective of Clinical Practice
Author(s): Emanuel Andres, Khalid Serraj, Mustapha Mecili, Georges Kaltenbach and Thomas VogelEmanuel Andres, Khalid Serraj, Mustapha Mecili, Georges Kaltenbach and Thomas Vogel
This article presents recent findings on cobalamin deficiencies due to food-cobalamin malabsorption or nondissociation of vitamin B12 from its carrier proteins syndrome. These findings might be of interest to medical practitioners. This disorder, for which a definitive consensus on the criteria for diagnosis is not yet available, is the leading cause of cobalamin deficiency in the elderly. In practice, food-cobalamin malabsorption is a diagnosis of exclusion, and requires the deductive elimination of all other causes of cobalamin deficiencies, particularly pernicious anaemia. The causes or associated disorders of food-cobalamin malabsorption are multiple and include gastric pathologies, Helicobacter pylori infections and certain drugs (biguanides and proton pump inhibitors). Depending on the disease aetiology.. View More»
DOI: 10.4172/2155-9864.1000108