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Journal of Stem Cell Research & Therapy
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Journal of Stem Cell Research & Therapy
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Margot Zoller

Margot Zoller

Margot Zoller Department of Tumor Biology University Hospital of Surgery, Germany

Biography
The focus on the lymphatic spread of tumor cells began with the establishment of a metastasizing rat pancreatic adenocarcinoma, the establishment of monoclonal antibodies selectively recognizing a metastatic subline and the subsequent expression cloning of a CD44 variant isoform (CD44v), the tetraspanin molecule D6.1A (homologue to the human CO029), the α6ß4 integrin, the cell-cell adhesion molecule D5.7A (homologue to EpCAM) and C4.4A, a molecule with homology to the uPA receptor.
Research Interest
Metastasis, Exosomes, Pancreatic cancer stem cells, Tetraspanins, EpCAM, Claudin-7, CD44v6