Manon Clavette
Canada
Research Article
Evaluation of C. albicans Adhesion and Growth
on Restorative Dental Materials Enriched or not with Fluoride
Author(s): Neftaha Tazi, Witold Chmielewski, Abdelhabib Semlali, Bouchaib Lamkhioued, Adil Akkouch, Manon Clavette, Mahmoud Ghannoum and Mahmoud RouabhiaNeftaha Tazi, Witold Chmielewski, Abdelhabib Semlali, Bouchaib Lamkhioued, Adil Akkouch, Manon Clavette, Mahmoud Ghannoum and Mahmoud Rouabhia
Candida albicans (C. albicans) is the most prevalent fungus in the human oral cavity and has been known as the primary cause of denture-related stomatitis. Candida cells have a high adhering potential to dental material in almost the same manner as to oral tissues, and they are known to form biofilm that leads to C. albicans resistance against antifungal drugs. The aim of this study was to investigate C. albicans adhesion and growth on different restorative dental materials and studied the effect of fluoride on C. albicans growth and morphological transition. To this end, C. albicans (Sc 5314) was cultured on acrylic resins, composite resin, and glass-ionomer materials. Growth was analyzed at various times using scanning electron microscopy analyses and cell proliferation assay. The effect of different concentrations (50 and 100 ppm) of exogenous fluoride on C. albicans growth and yea.. View More»
DOI:
10.4172/1948-5948.1000066