Journal of Microbial & Biochemical Technology

L Shwetha

Publications

• Research Article
  Screening and Molecular Characterization of Natural Fungal Isolates Producing Lovastatin
  Author(s): Upendra RS, Pratima Khandelwal, Z R Amiri, L Shwetha and Mohammed Ausim SUpendra RS, Pratima Khandelwal, Z R Amiri, L Shwetha and Mohammed Ausim S
  
  Aspergillus sp. is known to produce cholesterol reducing drug lovastatin. Limited investigations have been made on screening of high yielding strains from hitherto under-utilized natural sources. With this objective, in the present study, various fungal cultures (130 in number) were isolated from natural sources such as (soil from paddy fields, oyster mushroom beds from the fields and compost) from different regions of interiors of Karnataka and Tamil Nadu of India. All the isolates were identified through standard microbiological methods such as morphological, microscopic methods. These isolates were further cultured for the production of lovastatin through submerged fermentation process (SmF). The extract from each of the isolate was subjected to three replicates of UV spectrophotometry quantification (200-350 nm). Confirmation of the metabolite production was achieved through HPLC .. View More»
  DOI: 10.4172/1948-5948.1000094

  Abstract PDF