Journal of Pharmacovigilance

L González del Valle

Publications

• Research Article
  Dose-Tapering Of TNF Inhibitors in Daily Rheumatology Practice Enables the Maintenance of Clinical Efficacy While Improving Cost-Effectiveness
  Author(s): Dora Pascual-Salcedo, Plasencia Chamaida, Jurado Teresa, L González del Valle, Sabina Prado, Diego Cristina, Villalba Alejandro, Bonilla Gema, Martín Mola Emilio and Balsa AlejandroDora Pascual-Salcedo, Plasencia Chamaida, Jurado Teresa, L González del Valle, Sabina Prado, Diego Cristina, Villalba Alejandro, Bonilla Gema, Martín Mola Emilio and Balsa Alejandro
  
  Background The fact that biologics consume a growing portion of health care budget has resulted in an increased attention towards therapy optimization. One of the potential ways to optimize treatment is the down-titration of the administered drug dose. Objective To assess whether the clinical activity remains stable after dose tapering of TNF inhibitors in patients with low disease activity and to evaluate the potential benefit of this strategy on the treatment costs. Method A cohort of 77 patients with low disease activity treated with TNF inhibitors (TNFi) was monitored. The patients were studied over two time periods: .. View More»
  DOI: 10.4172/2329-6887.1000172

  Abstract PDF