Modern Chemistry & Applications

Koushik Mukherjee

Publications

• Research Article
  Synthesis of Chiral Gold Nanoparticle by Direct Reduction with L and D-Serine and Enhanced Anti-Mycobacterial Activity by D-Serine Protected Gold Nanoparticle
  Author(s): Koushik Mukherjee and Alok Kumar SilKoushik Mukherjee and Alok Kumar Sil
  
  Current situation demands more biocompatible and non-toxic nanostructures. Towards this the present study describes the synthesis of gold nanoparticle by direct reduction of tetrachloroauric acid with both D- and L-enantiomeric forms of the amino acid serine. The formation of nanoparticle was confirmed by examining different physical characteristics like surface plasmon resonance. Moreover, the retention of chirality of the reduced particle was also evident from circular dichroism spectroscopy experiment. In addition, the shielding of the nanoparticle by respective amino acid was confirmed by Scanning Electron Microscope and Energy Dispersive X-ray Analysis (SEM-EDAX). As D-serine is known to be active against Mycobacteria, examination of the biological activity of the D-serine protected particle was performed against the same. The result showed higher inh.. View More»
  DOI: 10.4172/2329-6798.1000165

  Abstract PDF