Indexed In
- Academic Journals Database
- Open J Gate
- Genamics JournalSeek
- JournalTOCs
- China National Knowledge Infrastructure (CNKI)
- Scimago
- Ulrich's Periodicals Directory
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- MIAR
- University Grants Commission
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Kießig ST
Kießig ST
Germany
Publications
-
Short Communication
Rationales for a Multi-Epitope Approach in an Autologous Renal Cell Cancer Tumor Vaccine
Author(s): Wittke S, Baxmann S, Fahlenkamp D, Schmiedeknecht G, Kebbel K and Kießig STWittke S, Baxmann S, Fahlenkamp D, Schmiedeknecht G, Kebbel K and Kießig ST
Objective: We report about a study according to a detailed characterization of an autologous tumor vaccine already used successfully in the immune therapy of renal cell carcinoma (RCC). The original paper was published in Onco Targets Therapy in 2016. This short communication summarizes the contents of the respective publication as well as shows new results of additional investigations by FACS-analysis. Method: A total of 133 tumor cell lysates (TCL) were investigated by ELISA, Western blots, topological proteomics and FACS analysis. Results: A total of 36 tumor-associated antigens (TAA) and cellular marker proteins were considered for analysis, whereof none was detectable in each tumor lysate. Moreover, the coincidental presence of potential danger signals was shown for HSP 60 and 70. Conclusion: .. View More»
DOI: 10.4172/2157-7560.1000327