Journal of Stem Cell Research & Therapy

Kenji Abe

Publications

• Research Article
  Autologous Peripheral Blood Stem Cells Increase the Telomere Length in Patient: A Case Report of 13 Patients
  Author(s): Ciro Gargiulo, Van H Pham, Kieu CD Nguyen, Vo LH Trieu, Thao H Duy, Kenji Abe, Sergey Aityan and Melvin ShiffmanCiro Gargiulo, Van H Pham, Kieu CD Nguyen, Vo LH Trieu, Thao H Duy, Kenji Abe, Sergey Aityan and Melvin Shiffman
  
  Telomere dysfunction, which leads to genomic instability, is assumed to play a major role in the development of degenerative diseases as Cancer, Multiple Sclerosis (MS), Amyotrophic Lateral Sclerosis (ALC), Alzheimer’s Disease (AD), dementia and diabetes. However, the few epidemiologic studies that assessed the relationship between telomere length in blood cells and autologous peripheral blood stem cells (PB-SCs) have been quite erratic. Cell senescence process, still remains an exciting biological process that is characterized by important structural and morphological changes that involves deviations and alterations in nuclear structure, DNA activity in protein processing and metabolism, and apoptosis resistance. The associations between telomere length from peripheral blood leucocytes before and after infusion with autologous PB-SCs were examined in 13 case studies that were c.. View More»
  DOI: 10.4172/2157-7633.1000352

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