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Joel Epstein
Joel Epstein
Canada
Publications
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Research Article
Effects of A Novel Disc Formulation on Dry Mouth Symptoms and Enamel Remineralization in Patients With Hyposalivation: An In Vivo Study
Author(s): Jessica Ho, Miracle Vania Firmalino, Afarin Golabgir Anbarani, Thair Takesh, Joel Epstein and Petra Wilder-SmithJessica Ho, Miracle Vania Firmalino, Afarin Golabgir Anbarani, Thair Takesh, Joel Epstein and Petra Wilder-Smith
Background: The goal of this study was to identify the in vivo effects in patients with hyposalivation of a novel slowly dissolving adhering test disc upon on enamel remineralization, oral biofilm, salivary production, pH and buffering, gingival health, and on self-evaluation of oral well-being. Methods: Five subjects with xerostomia wore custom made retainers carrying 5 demineralized enamel chips for periods of 1 week each. In 1 study arm, subjects used the test agent plus oral hygiene self-care; in the other they used oral hygiene self-care only, with a 1 week washout in between arms. The treatment sequence was randomized. Before and after each study arm Plaque Index (PI), Gingival Index (GI) and Sulcus Bleeding Index (mSBI) were recorded. Clinical plaque staining was quantified using digital image analysis. Saliva production, pH and.. View More»
DOI: 10.4172/2161-1122.1000411