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Jaymesh Thadani
Jaymesh Thadani
India
Publications
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Review Article
A Novel Stem Cell Paradigm: Past Controversies, Present Challenges & Future Prospects
Author(s): Shivani Vakodikar, Jaymesh Thadani and Prashant KshatriyaShivani Vakodikar, Jaymesh Thadani and Prashant Kshatriya
Stem Cell therapeutics is a revolutionary change in the world of modern medicine. These magical bullets have evolved as alternative therapeutic modality to conventional method. Different countries have passed legislation to undertake the human embryonic stem cell research. Developed countries like USA and, Australia have banned the exploration of hESCs for research purpose. While on the other hand, developing countries have made stringent regulatory approvals and permitted the research. To avoid ethical conspiracy, induced Pluripotent stem cells with same potential with that of hESCs raised scientific breakthrough. The major flaw related to iPSCs was teratoma formation. Thus to avoid hESCs controversy and loopholes of iPSCs, application of adult stem cells came into existence. To manufacture clinical grade stem cells, cell identity, purity and genomic stability for long term culturing.. View More»
DOI: 10.4172/2157-7633.1000403