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Jackleen Raafat Awadallah Hanna

Jackleen Raafat Awadallah Hanna
Medical Biochemistry Department,
Medical Division, National Research Center

  • Thesis
    Expression of CD95 in Acute Lymphocytic Leukemia (ALL) in Egyptian Children before and after Treatment
    Author(s): Jackleen Raafat Awadallah HannaJackleen Raafat Awadallah Hanna

    Acute lymphocytic leukemia (ALL) is a malignant disorder common among children. Apoptosis is a morphological process that leads to controlled cellular self-destruction and defective apoptotic pathways are greatly involved in tumor formation, progression, and metastasis. Apoptosis is the primary mechanism through which most chemotherapeutic agents induce tumor cell death. The purpose of this study was to monitor the expression of pro- and anti-apoptotic proteins CD95 and Bcl-2 as well as copper and zinc levels in the peripheral blood of children with acute lymphocytic leukemia prior to, and six months after starting chemotherapy. The study was performed on twenty five children attending the outpatient clinic of the National Cancer Institute – Cairo University. Ten normal children were included in the study and considered as control group. Results showed that Total Leukocyte Count.. Read More»
    DOI: 10.4172/2155-9864.1000250

    Abstract PDF