Journal of Stem Cell Research & Therapy

Guifang Zeng

Publications

• Research Article
  Therapeutical Comparison of Mesenchymal Stem Cells from Different Tissues of Human Placenta in the Treatment of Mice with Acute Hepatic Failure
  Author(s): Guifang Zeng, Qiongshu Li, Hongfang Ju, Xin Zhou, Jiaolian Zhu, Xiaoping Zeng, Yixin He, Chan Li, Jia Liu, Chunfeng Wu, Tenglong Yan, Man Wu, Jingyi Gan, Wei Li, Jiuwei Cui, Xiang Hu, Jifan Hu and Tao LiGuifang Zeng, Qiongshu Li, Hongfang Ju, Xin Zhou, Jiaolian Zhu, Xiaoping Zeng, Yixin He, Chan Li, Jia Liu, Chunfeng Wu, Tenglong Yan, Man Wu, Jingyi Gan, Wei Li, Jiuwei Cui, Xiang Hu, Jifan Hu and Tao Li
  
  Mesenchymal stem cells (MSCs) are powerful sources for cell therapy in regenerative medicine due to their capacity for self-renewal, multilineage differentiation, and immune modulation. Placenta-derived stem cells (PDSCs) have been recently suggested as alternative sources of stem cells. However, comparative studies to decide the most suitable cells for cell-based therapeutics are largely lacking. This study attempted to compare the potential of PDSCs in the treatment of mice with acute hepatic failure (ALF). We isolated four types of PDSCs, including the fetus-derived chorionic villi MSCs (CV-MSCs), Wharton’s jelly umbilical cord MSCs (WJ-MSCs) and amnion MSCs (AE-MSCs), and the maternally derived decidua basalis MSCs (DB-MSCs). We found that all PDSCs showed similar biological properties, including morphology, specific surface antigen, proliferation, and multipotent differenti.. View More»
  DOI: 10.4172/2157-7633.1000316

  Abstract PDF