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Gomes R
Gomes R
Portugal
Publications
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Case Report
Desensitization to Allopurinol in Localized and Systemic Hypersensitivity Reactions
Author(s): Gomes R, Ribeiro F, Faria E, Loureiro C and Segorbe-Luís AGomes R, Ribeiro F, Faria E, Loureiro C and Segorbe-Luís A
Introduction: Allopurinol is, by far, the most frequently prescribed drug for the treatment of hyperuricemia, and the lack of alternatives makes, in case of a reaction, a desensitization procedure to be considered. With this survey, we aimed to do a characterization of patients with hypersensitivity (HS) reactions to allopurinol, who endured desensitization procedures. Material and methods: Retrospectively, we analyzed the medical files of a group of patients that fit into our objective and were observed in our Department of Immunoallergology of Coimbra University Hospital, between 2007/2012. Demographic data, pathology underlying all prescriptions and concomitant diseases/regular medication, the desensitization protocol and all adverse reactions were taken into consideration. Results: Six out of seven patients were male, aged from 37 to 79 (mean age of 64 ± 14 .. View More»
DOI: 10.4172/2155-6121.1000138