Biochemistry & Analytical Biochemistry

Gad Ziad S

Publications

• Research Article
  Chitinase-3-Like Protein1 (YKL-40) as Biomarker in Serum of Egyptian Breast Cancer Females
  Author(s): Shaker Olfat G, Nassar Yasser H, Kamel Moataz M, Gad Ziad S and Elantably Ahmed MShaker Olfat G, Nassar Yasser H, Kamel Moataz M, Gad Ziad S and Elantably Ahmed M
  
  Background: YKL-40 is a recently discovered human glycoprotein which is related in amino acid sequence to the chitinase protein family, but has no chitinase activity, its expression was shown to be highly expressed in breast cancer Aim: we aim to detect level of YKL-40 in metastatic and non-metastatic breast cancer patients and comparing the results with fibroadenoma patients and normal females. Methods and materials: 116 female patients were enrolled in this study and they are divided into 37 patients with fibroadenoma, 43 non-metastatic & 36 metastatic patient. Thirty healthy females were also included and served as control. YKL-40 level is detected in serum of studied groups using ELISA kit provided from Quantikine R&D systems, Minneapolis, USA. Results: There is statistical significant difference regarding YKL-40 level between the control group versus nonm.. View More»
  DOI: 10.4172/2161-1009.1000149

  Abstract PDF